Dangerous Drugs - Requip

Requip, or Ropinirole, is a non-ergoline dopamine agonist manufactured by GlaxoSmithKline. It is used in the treatment of Parkinson's disease, and is also the only medication in the United States with an FDA-approved indication for the treatment of restless legs syndrome. Requip works by mimicking the effects of the neurotransmitter dopamine, which helps people control their movements and increases feelings of happiness and satisfaction. Because Parkinson's Disease occurs due to a lack of dopamine in certain areas of the brain, Requip can help ease some of the symptoms associated with Parkinson' s and Restless Leg Syndrome. Requip is currently one of the most prescribed drugs in the dopamine agonist class of drugs.

Requip's link to compulsive behavior is thought to result from the rush that dopamine can give in anticipation of a reward or excitement, such as gambling. Depending on a patient's health factors and the levels of the drug prescribed, Requip has been connected with low blood pressure, falling asleep with no warning, and hallucinations. Requip has also been shown to exacerbate the likelihood of Parkinson's patients to develop other conditions, such as melanoma, confusion, compulsive behaviors, and retinal degeneration.

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